Developments in laboratory diagnosis of chromosomal abnormalities.
نویسنده
چکیده
The development of chromosome banding techniques has made possible the detailed analysis of human chromosomes. A vast body of knowledge has accumulated during the last few years as a result of their application in biology and medicine.
منابع مشابه
Chromosomal Abnormalities in Regions 8q22 and 13q32 Associated with Different Disorders in an Iranian Family
Chromosomal abnormalities are major causes of infertility, miscarriage and birth of handicapped progeny. In human live births, the prevalence of a chromosome aberration is ?0.5% and, of these, 0.1–0.3% correspond to structural chromosome rearrangements such as translocations, inversions, insertions and deletions .Our proband is an infant who had died 4 hours after birth due to a variety of abno...
متن کاملP-94: Male Infertility in China: Laboratory Finding for AZF Microdeletions and Chromosomal Abnormalities in Infertile Men from Northeastern China
Background: To investigate the frequencies of AZF microdeletions and chromosomal abnormalities in infertile men from Northeastern China. Moreover, to compare the prevalence of these abnormalities with other countries and regions in the world. Materials and Methods: 305 infertile men were enrolled. A complete semen analysis and reproductive hormones were measured according to standard methods. M...
متن کاملChromosomal Analysis of Couples with Repeated Spontaneous Abortions in Northeastern Iran
Background Cytogenetic study of reproductive wastage is an important aspect in determining the genetic background of early embryogenesis. Approximately 15 to 20% of all pregnancies in humans are terminated as recurrent spontaneous abortions (RSAs). The aim of this study was to detect chromosome abnormalities in couples with RSAs and to compare our results with those reported previously. Materia...
متن کاملChromosomal Abnormalities in Iranian Infertile Males who are Candidates for Assisted Reproductive Techniques
Background The present study offers our contribution on the topic by a retrospective analysis of the prevalence of chromosomal abnormalities in a population of Iranian infertile men attending assisted reproduction programs. MaterialsAndMethods Cytogenetic analysis was performed according to standard methods on cultured cells obtained from the patient peripheral blood. In all, 874 files belongin...
متن کاملAssociation of Fetal and Parental Chromosomal Abnormalities with Congenital Anomalies
Background & Aims: Chromosome abnormalities are a major cause of miscarriage and neonatal mortality. The present study aimed to determine the association of fetal and parents chromosomal abnormalities with congenital anomalies. Methods: A cross-sectional study was performed in a tertiary referral center (Afzalipour Hospital) over 16 months period (2011-2012). The study groups consisted of 77 fe...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Annals of clinical and laboratory science
دوره 5 5 شماره
صفحات -
تاریخ انتشار 1975